Black stools are caused by physiologic factors, taking omeprazole enteric-coated tablets is not useful, and taking omeprazole enteric-coated tablets is useful when they are caused by pathologic factors such as gastritis and gastric ulcer. There is no point in taking omeprazole enteric-coated tablets when the patient is suffering from physiologic factors such as consuming too much blood products. If the patient due to gastritis, gastric ulcer and other pathological factors lead to upper gastrointestinal bleeding, taking omeprazole enteric-coated tablets can effectively relieve ulcer aggravation, reduce upper gastrointestinal bleeding, is useful. Therefore, patients taking omeprazole enteric-coated tablets for black stools is effective or not needs to be combined with the patient’s specific condition to decide, the patient needs to be under the guidance of the physician to take medication, not blindly choose drugs for treatment.