There is no most effective drug for treating GERD, and there are individual differences in the effectiveness of drugs. GERD is now mainly treated with medication, generally applying acid suppressants, mucosal protectants and prokinetic agents and other drugs.
1. Acid suppressants: such as proton pump inhibitors (omeprazole, rabeprazole, etc.) and H2 receptor antagonists (ranitidine, etc.) can effectively inhibit the secretion of gastric acid, reduce the concentration of gastric acid, and relieve the symptoms of reflux. However, pregnant women, lactating women, patients with hepatic and renal insufficiency should be used with caution.
2. Prokinetic drugs: such as domperidone and mosapride. When the effect of acid-suppressing treatment is unsatisfactory, consider the combined application of prokinetic drugs, especially for patients with delayed gastric emptying, which can promote gastric emptying, facilitate the discharge of gastric acid and relieve reflux. However, adverse reactions such as anxiety, headache, diarrhea and skin rash may occur when using them, and allergic individuals should use them with caution.
3. Mucosal protection drugs, such as colloidal bismuth, can form a protective layer at the damaged mucous membrane, reduce the corrosion of the mucous membrane by gastric acid and relieve the symptoms of heartburn. However, the symptom of black stool may appear when using it, which usually disappears after stopping the medicine.
Gastroesophageal reflux relief is recommended to seek timely medical attention and reasonable treatment under the guidance of a doctor. Drugs must be taken strictly according to the doctor’s instructions, not self-medication, so as not to delay or even aggravate the condition.