Whole body blood exchange is generally referred to as medical plasma exchange, which costs around $6,000 to $8,000 a time. Plasma exchange refers to directing the patient’s blood outside the body, separating plasma and cellular components by centrifugation or membrane separation, discarding the plasma, and infusing back into the body the cellular components as well as the required replenishment of albumin, plasma, and balancing fluids, etc., in order to remove disease-causing substances in the body, including auto-antibodies, immune complexes, cholesterol, bilirubin, medications, and poisons. It is mainly used in the treatment of acute progressive glomerulonephritis, acute toxic poisoning and other diseases. Plasma replacement requires a variety of instruments and equipment in addition to plasma substitutes such as albumin and balancing fluids, making it relatively expensive. Systemic blood transfusion is an invasive operation with high operational requirements and risks, and needs to be closely monitored by a doctor. The relatively high cost of total body exchange in adults is related to the therapeutic supplies applied to the patient during the procedure, which needs to be carried out after the physician evaluates the patient’s condition.