Spironolactone and furosemide can be taken in full half tablets, both spironolactone and furosemide are diuretic medications. The efficacy of the two drugs is as follows: If spironolactone is used to lower blood pressure and improve cardiac function, it is usually used half a tablet to one tablet per day, and if it is used for diuresis, which is a low potency diuretic, the dosage is increased to one to five tablets. Furosemide treats hypercalcemia, acute hyperkalemia with renal failure, hypertension, and edematous disorders at a routine starting dose of 20 to 40 mg daily. Spironolactone can cause adverse reactions such as nausea, vomiting, stomach cramps, and diarrhea, and is contraindicated in those who are allergic to the product and in patients with hyperkalemia. Furosemide has postural hypotension, shock, hypokalemia, hypochloremia and other adverse reactions, is prohibited for those who are allergic to sulfonamides and thiazide diuretics, pregnant women, especially in the first three months of pregnancy should be avoided; breastfeeding women should be used with caution. It is recommended to take under the guidance of a doctor to avoid causing adverse reactions.