Intraductal papilloma grade 4c, should improve the pathology and other tests, to confirm the diagnosis of the disease before conservative treatment or surgical treatment. The cause of intraductal papilloma is related to abnormal estrogen secretion level and genetic factors. Clinical symptoms include bloody nipple discharge and a mass under the nipple. With the prolongation of the disease history, there is a possibility of cancerous transformation. In clinical work, the nature of the lesion is graded according to ultrasound, molybdenum target and other imaging examinations. It is generally categorized into 7 grades, with grade 1 to 3 being the category of benign lesions, grade 4 being suspected malignant lesions, and grade 4 being subdivided into three subgrades of a, b, and c. The current patient is grade 4c, indicating the possibility of cancer. The diseased tissue is excised or a portion of the diseased tissue is obtained through a puncture needle and then pathologically examined. If the pathology result is benign, conservative treatment can be taken for the time being, and the patient needs to be closely followed and observed. The examination is repeated once every three months or so to monitor the development of the lesion. If the pathological result is malignant, surgery is needed to remove the lesion, and then supplemented with subsequent radiotherapy, targeted drug therapy, endocrine therapy and other measures, so as to stabilize the condition.