The usual term for tranquilizing the mind usually refers to tranquilizing brain solution. An Shen tonic brain liquid can be helpful for insomnia, but the treatment of insomnia cannot simply rely on An Shen alone. An Shen is a kind of Chinese patent medicine containing ingredients such as sour date palm, Chuanxiong, Zhi Mu, Mai Dong, He Shou Wu, Wu Wei Zi, Dan Shen, Fu Ling, etc. Its main function is to nourish blood and nourish yin, nourish the heart and calm the mind, and is used for yin and blood deficiency, palpitation and restlessness, five heart trouble and heat, night sweating and tinnitus, and is helpful for those who have insomnia and dreaminess. However, insomnia is a clinical manifestation caused by a variety of complex factors, mainly manifested as difficulty in falling asleep, difficulty in waking up and falling asleep again at night, and low maintenance of sleep time, etc. The causative factors include physiological, psychological, environmental and other changes, as well as drugs, neuropsychiatric and somatic disorders. Common causes include family genetic factors, stress and life events, lifestyle problems, self-characteristic personality, previous illnesses and special medications, and advanced age of women. The treatment of insomnia includes psychotherapy, medication, physiotherapy, Chinese medicine and comprehensive treatment. First of all, bad sleep behaviors and concepts should be prevented and corrected, and the triggering factors of insomnia should be dealt with, and medication should be supplemented if necessary. Therefore, for patients with insomnia and dreaminess caused by deficiency of Yin and Blood, An Shen has certain therapeutic effects and can improve sleep quality to some extent with proper administration, but it is not necessarily effective for other types of insomnia.