In general, long-term use of entecavir will not accelerate the occurrence of cirrhosis, but will also have a certain improvement effect on cirrhosis. Entecavir has better efficacy in the treatment of hepatitis B. It is a common medication for the treatment of hepatitis B. It can play a certain therapeutic effect on liver patients, and hepatitis B patients may still form cirrhosis of the liver further, while entecavir will not accelerate the occurrence of cirrhosis of the liver. Entecavir medication will have a certain effect on the hepatitis virus in the body, but there will be certain adverse reactions, such as nausea and vomiting, generalized fatigue, etc., which is a normal phenomenon, do not have to worry too much. According to current data, the therapeutic effect of entecavir is relatively good, basically there is no production of other diseases after taking entecavir. However, to take entecavir, you must follow the doctor’s instructions, not indiscriminate use of drugs, otherwise it is likely to cause some damage to the body. If any abnormality occurs during the period of taking the medicine, it is recommended to consult a doctor in time.