According to the diagnostic points recommended by the World Health Organization (WH0), Crohn’s disease can be diagnosed according to the following criteria, based on the exclusion of chronic intestinal infections such as intestinal tuberculosis, amebic dysentery, Yersinia pestis infection, intestinal lymphoma, diverticulitis, ischemic enterocolitis and leukoaraiosis. — Exclusion of other diseases is a prerequisite for the diagnosis of Crohn’s disease WHO’s diagnostic criteria are: ① Discontinuous or regional intestinal lesions; — What we call segmental lesions ② Intestinal mucosa with pavement pebble-like manifestations or with longitudinal ulcers; ③ Total inflammatory intestinal lesions with masses or strictures; – in the absence of surgery, thickening of the intestinal wall can be suggested on CT and MRI ④ nodular disease-like non-caseating granuloma; – this is the most typical presentation pathologically, but it is rarely seen in specimens obtained by colonoscopy ⑤ fissure or fistula; ⑥ anal lesion with refractory ulcer, anal fistula or fissure. Those with WH0 diagnostic points ①②③ are suspected, and the diagnosis can be confirmed by adding any one of the three items ④⑤⑥. If you have item ④, the diagnosis can be confirmed by adding any two of items ①, ② and ③.