Black spots are usually related to seborrheic keratosis, chloasma and other diseases, and need to be treated according to the cause of the disease. Patients can follow the doctor’s instructions to use hydrogen peroxide, hydroquinone and other drugs for treatment. 1. Seborrheic keratosis: seborrheic keratosis may cause dark spots, and it is recommended that patients follow the doctor’s instructions to use 40% hydrogen peroxide, liquid nitrate-zinc composite and other solutions, which can help to repair the skin lesions and alleviate the local symptoms, and can also follow the doctor’s instructions to carry out freezing and laser treatment. 2. Melasma: dark spots are considered to be related to melasma, patients should follow the doctor’s instructions to use hydroquinone, deoxyarbutin and other decolorizing agents, which can help reduce the color of dark spots. It can also be used externally with azelaic acid ointment as prescribed by doctor to inhibit the synthesis of microbial protein, which can help to remove the dark spots, maintain a good life and routine, pay attention to sunscreen, and undergo laser treatment if necessary. There are many causes of dark spots, patients should go to the hospital for consultation, and choose relevant drugs for treatment according to the cause of the disease and follow the doctor’s instruction, and can also use freezing, laser and other ways to help remove the lesions, patients can choose the appropriate treatment according to their personal situation and under the guidance of the doctor.