Polymerized acne is a more serious type of acne and can be treated with topical medications, oral medications, and physical therapy. 1. Topical medication: topical cream of vitamin C, adapalene gel can be used to promote the abnormal keratinization of local hair follicles to return to normal, and to reduce sebum secretion. For patients with obvious inflammation, antibacterial and anti-inflammatory drugs can be used, such as benzoyl peroxide gel, clindamycin gel or fusidic acid cream. 2. Oral medication: Minocycline, doxycycline, clarithromycin, etc. can be taken orally to promote the dissipation of polymerized acne. If the symptoms are more serious, oral treatment with isotretinoin or glucocorticosteroids such as prednisone or trimethoprim can also be considered. 3. Physical therapy: Localized irradiation with red and blue light, intense pulsed light, or chemical peeling with fruit acid or salicylic acid can also promote the dissipation of polymerized acne. It is recommended that patients with polymerized acne go to the hospital for consultation, and the formulation of specific treatment plans, including the choice of drugs, dosage, treatment course, etc. should be carried out under the guidance of a professional physician, do not use drugs arbitrarily, so as to avoid delaying the condition or the occurrence of side effects.