The main reasons for taking two kinds of epilepsy drugs and still having seizures include the primary cause of epilepsy or triggers have not been eliminated, and inappropriate types, dosages, and times of taking the drugs, and other factors. 1. The primary cause or trigger of epilepsy has not yet been eliminated: some epilepsy may be caused by intracranial diseases such as intracranial tumors and encephalitis. If the primary intracranial disease has not yet been treated or controlled, epileptic seizures may occur even when taking two kinds of drugs. In addition, patients may also have seizures if they are not careful to avoid triggers such as staying up late or drinking alcohol while taking the medication. 2. Inappropriate type, dosage and time of medication: anti-epileptic drugs need to be chosen according to the specific type of epilepsy, and can’t be controlled if they are taken inappropriately. At the same time, if patients take medication irregularly, the blood concentration fluctuates greatly, especially at night, clinical seizures are likely to occur. In addition, even if you take two drugs but the dose is not enough, it will also lead to recurrent seizures. When seizures still occur even after taking two medications, it is recommended to go to the neurology department of a regular hospital for a relevant examination and further treatment under the guidance of an experienced physician.