Postmenopausal osteoporosis often occurs in the elderly, especially in women, and senile osteoporosis often occurs in elderly men after the age of 70. When osteoporosis occurs, suffering a slight external force, such as sneezing, falling, or lifting something, or turning over or sitting down too hard, etc., can cause vertebral compression fractures, which are very common in clinical practice. There are two types of treatment: 1. Conservative treatment: the method commonly used in orthopedics in the past. After the injury at the site of the injury that is the most obvious part of the pain with a cushion, lying flat on the cushion, relying on the anterior longitudinal ligament tension force in front of the vertebral body to correct the wedge-shaped lesion of the compression fracture vertebrae, generally 3-5 days can be removed from the cushion, bed rest for 2 to 3 months, monthly review, until the fracture healed, but the effect is not good, the patient is very painful, mainly when lying flat on the cushion cushion skin The pain is mainly due to the pressure on the skin when lying flat on the mat, and the fractured vertebrae are also slightly repositioned due to the high mat resulting in pain, and many patients cannot persevere. Many patients, especially those with underlying diseases such as cardiopulmonary dysfunction, cannot survive such long bed rest and may have life-threatening complications due to these complications. Summary: Advantages: low initial treatment cost, no surgery. Disadvantages: very painful and long process, requires multiple people to stay with the patient for a long time, and risky, often life-threatening due to complications. 2, minimally invasive surgery: percutaneous balloon expansion, vertebral body retrobulbar plasty. The operation is not open, only skin puncture, local anesthesia, about 40 minutes to end, the patient can be normal activities on the next day after surgery. It provides good pain relief and prevents further loss of vertebral body height and further increase in the angle of fracture in the future. It is currently a good treatment for osteoporotic vertebral compression fractures in the elderly. Summary: Advantages: minimally invasive, no incision, short treatment time of 40 minutes, fast pain relief, good results. Disadvantages: high initial cost and risk of bone cement leakage. Medication anti-osteoporosis treatment is mandatory regardless of the method chosen. Classic regimen: Calcium D, oral, one tablet a day, and salmon calcitonin, nasal spray, once a day. A short course of oral aminoglutethimide for 3-5 days is sufficient.