Herpes on the palm of the hand is very itchy generally refers to blisters with itching, can be considered with sweat herpes, palmoplantar pustulosis or tinea versicolor and other skin lesions related. 1. sweating herpes: the etiology of its occurrence can be related to neuropsychiatric factors, local irritation, allergies and other factors, the skin appeared deep in the corn-sized blisters, accompanied by varying degrees of itching as well as a burning sensation, blisters clear or turbid pulp, in the blisters after drying, there is the emergence of dandruff. 2. Palmoplantar pustulosis: it may be a manifestation of palmoplantar pustular psoriasis or an allergic reaction caused by pus-filled bacteria elsewhere in the body. The blisters appear in the palms of the hands at the beginning, which may rapidly turn into pustules, and the neighboring pustules may be fused, accompanied by itching or burning pain in varying degrees. 3. ringworm: generally higher incidence in summer, when the hands have superficial fungal infection, can be seen in the palm, between the fingers and other parts of the blisters, for the pinpoint size of the deep in the blisters, blister wall is thicker is not easy to break, the blister liquid is clearer in the drying and absorption of desquamation can be seen, accompanied by obvious itching. Itchy blisters appear on the palm of the hand, it is recommended to consult a doctor in time, and timely compliance with the doctor’s instructions for treatment.