Low total cholesterol is mostly caused by liver disease, high metabolic disease or malnutrition. 1. Liver disease, when suffering from chronic hepatitis, cirrhosis, liver cancer and other diseases, it will lead to lower cholesterol than normal. 2. High metabolic diseases, when suffering from diffuse goiter, hyperthyroidism, tuberculosis and other diseases, will lead to increased nutritional consumption of the body, cholesterol lowering performance. 3. Malnutrition, mostly caused by women dieting in order to pursue body shape, or dietary habits that lead to less meat intake and other reasons. It is recommended to consult a regular hospital in a timely manner and under the guidance of a professional physician to carry out relevant examinations and treatments.