Plantar vein thrombosis requires pain medication such as ibuprofen, aspirin and microcirculation improvement drugs such as sulodexide. 1. Painkillers: Plantar vein thrombosis can cause localized pain, which can be treated with painkillers such as ibuprofen and aspirin under doctor’s supervision, and can also play the role of anti-platelet aggregation. 2. Drugs to improve microcirculation: you can use topical drugs under the guidance of a doctor, such as epidermal growth factor, and take drugs to improve microcirculation, such as sulodexide, which can play a role in repairing the endothelial cells, but also has an anti-inflammatory and anti-thrombotic effect. In the course of treatment, you need to communicate with your doctor and cooperate with him or her, and if there are any abnormalities, you need to go to the hospital in time to avoid delaying your condition.