Radiation therapy is one of the most effective treatments for head and neck tumors. In the process of radiotherapy, parotid gland and salivary gland are within the scope of irradiation, so the function of parotid gland and salivary gland is inhibited and saliva is reduced, while at the same time, radiation also directly damages the capillaries of oral mucosa, narrowing or blocking the microcirculatory vessels in the irradiated area, causing local circulatory disorders, resulting in congestion and edema of mucosal surface, compression of peripheral nerve causing pain, infiltration and exudation of mucosal epithelial cells to form white film, and radioactive mucosal reaction occurs. The oral mucosal reaction is known as oral ulcer.
Oral ulcers can cause pain in the patient’s mouth and difficulty in eating in light cases; in heavy cases, they can cause water-electrolyte disorders and nutritional disorders, resulting in interruption of radiotherapy and affecting the implementation of the treatment plan. The more painful it is, the more patients are afraid to clean their mouths, which leads to the breeding of oral bacteria and further aggravates oral mucositis.
What to do?
Don’t worry, all medical and nursing staffs in head and neck tumor Ⅰ ward have a wonderful trick to deal with oral ulcers with “four treasures”!
”One treasure”
The “green genie” Aloe Curaçao, not only can beauty it can also stop bleeding, fast healing wounds, pre-prevention, later repair it can package.
Aloe vera: Aloe vera gel polysaccharide can promote the formation of granulation, and through the decomposition of enzymes to have the dead cells, infected tissues and other removal, can promote wound healing, rapid and effective hemostasis, wounds completely healed without leaving scars.
Usage.
1.Usually used in the early stage of mouth ulcer formation;
2.Cut an appropriate amount of Aloe Vera and take out the original aloe vera solution or remove the skin and slice it;
3.Incorporate the aloe vera solution into the mouth or put the sliced aloe vera on the red, swollen or ulcerated surface.
Caution.
1.Clean your mouth before using Aloe Vera;
2.Include or apply the aloe vera into the mouth after 5-10 minutes of use and spit out not to eat.
”Two treasures”
Small and cute goldin peptide, don’t look at its small size, but it has big energy. Repair epidermis a cover.
Goldin peptide: colorless and transparent liquid for external use, the active ingredient is recombinant human epidermal growth factor (rhEGF), with 10% glycerin and 1.0% mannitol as protective agent, which has the function of promoting the synthesis of DNA, RNA and hydroxyproline in the process of skin and mucous membrane wound tissue repair. It can accelerate granulation tissue generation and epithelial cell proliferation on the trauma surface, thus shortening the healing time of the trauma surface.
Usage: Usually used in the middle stage of mouth ulcer, rinse the mouth and spray evenly in the mouth.
Note: It needs to be stored in the refrigerator at 2-8℃ under refrigeration.
”Three Treasures”
”Red and white double fury” healing effect, cleaning, antibacterial, pain relief, repair the oral mucosa in one hand package
”Red Fury”: the main ingredients are vitamin B12, gentamicin, dexamethasone and lidocaine.
Vitamin B12 is an indispensable substance for RNA synthesis, it can accelerate the proliferation of granulation tissue and epithelial tissue regeneration, and has significant repair function for damaged skin mucous membrane epithelial cells and vascular endothelial cells;
Gentamicin can kill Gram-negative bacilli and anaerobic bacteria in the oral cavity and eliminate oral inflammation;
Dexamethasone can reduce local mucosal exudation, edema, capillary dilation, leukocyte infiltration and phagocytic response;
Lidocaine is a local anesthetic with obvious analgesic effect, which helps to relieve the symptoms and reduce the pain caused by mucosal reaction.
The main component of “White Sage” is sodium bicarbonate, which is alkaline and can effectively improve the acidic environment in the mouth to reduce fungal infections.
Usage.
1.Use from the first radiotherapy until the end of radiotherapy for three to six months;
2.Rinse the mouth with “red water” before eating to relieve pain and repair the oral mucosa;
3.After eating, rinse the mouth with “white water” to achieve the effect of cleaning and antibacterial;
4, each gargle time should not be less than 3 minutes.
Note:
1, “red and white double water” is valid for 76 hours, not allowed to use after the expiration date;
2, in order to ensure that the “red and white double water” clean and effective, please prepare a gargle cup in several times to take.
”Four treasures”
Transparent gel Bevoxin, ulcer healing, good wound repair effect
Bevoxin: colorless transparent gel, the active ingredient is recombinant bovine basic fibroblast growth factor, made from E. coli containing highly efficient expression of bovine basic fibroblast growth factor gene, after fermentation, isolation and high purification. It has the effect of promoting the repair and regeneration of cells derived from mesoderm and ectoderm (such as epithelial cells, dermal cells, fibroblasts, vascular endothelial cells, etc.). It can promote capillary regeneration, improve local blood circulation and accelerate the healing of wounds.
Usage.
1.Start using in the middle of mouth ulcer;
2. Clean the mouth before use, rinse the mouth with saline, and apply to the mouth ulcer surface with a cotton swab once a day or as prescribed by the doctor.
Attention.
1.This product is sterile packaging, please cover tightly immediately after use, and try to keep it free of contamination during the operation;
2. It should be kept in refrigerator at 2-8°C and protected from light, not in high temperature or frozen environment;
3, high concentration of iodine, alcohol, hydrogen peroxide, heavy metals and other protein denaturants may affect the activity of this product, rinse the mouth with saline before use.