Red raised pimples on the body at night especially itchy may be papular urticaria, scabies, etc., need to clarify the diagnosis, choose the appropriate drugs, such as glucocorticoids, antihistamines, etc., for treatment. 1. papular urticaria: after the diagnosis of this disease, you can use topical antipruritic agent treatment, such as glycerine lotion, zinc oxide ointment, etc.; or topical glucocorticoid treatment, such as hydrocortisone, dexamethasone, etc.; intense itching, oral antihistamine treatment, such as loratadine, cetirizine, etc.. 2. Scabies: It can lead to red papules on the vulva, fingernails, abdomen and other parts of the body, accompanied by intense itching at night. It is necessary to use external insecticides such as sulfur ointment and other treatments; if the itching is serious, oral antihistamine treatment, such as loratadine, ebastine and so on. It is recommended that patients go to a regular hospital, after a clear diagnosis, follow the doctor’s instructions and reasonable use of medication, not blindly self-medication.