If the diagnosis of gallbladder stones is clear and there is a history of acute attacks, in principle, surgical treatment should be adopted. Although gallbladder stones themselves are not complicated, the possibility of acute onset, secondary bile duct stones, biliary pancreatitis, intestinal gallbladder fistula, and even gallbladder cancer, plus the fact that gallbladder stones are very common, should be given sufficient attention! The accepted and effective standard treatment for gallbladder stones is still laparoscopic cholecystectomy, which can solve the problem satisfactorily without associated comorbidities. Gallstone extraction is a useful attempt to treat gallbladder stones, but it is still very controversial whether it is a reasonable, effective and complete solution to the problem, because the stones that can be found are only one of the results of the disease progression, and the specific causes of gallbladder stones are not yet completely understood, except to say that the formation of gallbladder stones is related to many factors. The removal of gallbladder stones by invasive methods alone does not actually change all the underlying conditions associated with stone formation, the stone formation process is not interrupted, the stone forming organ and its pathological changes remain, while the vigilance of the patient, the family and even the medical staff concerned about the possible serious consequences of disease progression (e.g. later gallbladder cancer) is greatly relaxed! If the gallbladder is functioning well and the patient is able to understand the recurrence of stones, an experimental laparoscopic biliary conservation surgery can be performed. Minimally invasive surgery is a trend nowadays and can be performed successfully in most patients with gallbladder stones. However, if there are obvious structural variations in the gallbladder or bile duct system, special pathological changes in the gallbladder, or suspected gallbladder occupancy, it is prudent to decide whether to opt for minimally invasive surgery, and it is best to have a preoperative magnetic resonance cholangiography (MRCP) or CT examination. If the gallbladder function is basically lost before surgery, the removal of the gallbladder will have no effect on the digestive function; if the gallbladder function is partially preserved, there may be an increase in the number of stools after surgery. In terms of diet, Western medicine does not pay attention to the avoidance of food, but if there are other concomitant diseases, it is a different story. Adverse reactions after cholecystectomy are a special category! In short, all surgeries cause trauma to the body, there are risks, and some medical conditions related to trauma and tissue repair may occur, but the probability of serious problems is small as long as basic medical principles are followed for the specific implementation of each treatment step. Of course, the patient’s age, physical condition, specific medical condition, and the presence of serious concomitant diseases also have a great deal to do with the post-operative recovery process and status, so please consult with your doctor for details.