Guanmutong was used in the original Gentian Liver Disease Pill, which had nephrotoxicity when taken for a long time, but now Guanmutong is replaced by Mutong, and nephrotoxicity has not been reported. However, it should be noted that long-term use should be judged according to the patient’s condition under the diagnosis of a professional physician. Gentian Liver Pill is a common Chinese medicine, its main ingredients are gentian, chaihu, scutellaria, zejiao, fried gardenia and so on. It has the efficacy of clearing the liver and gallbladder and inducing dampness and heat. It is used in treating damp-heat in the liver and gallbladder (damp-heat evils accumulated in the liver and gallbladder), dizziness and redness of the eyes (dizziness and redness of the eyes), tinnitus and deafness, dystocia (pain in the area of coats of arms and ribs), bitterness in the mouth, redness and astringency of the urine (feverish, unobstructed and painful sensation during urination), and damp-heat leucorrhoea. It has not been documented that taking this product now will injure the kidneys, and its adverse effects and contraindications are not yet clear. It should be used with caution in pregnant women, the elderly and the infirm, and those with loose stools. It is not suitable to take tonic Chinese medicine at the same time during the period of taking the medicine. Avoid eating spicy and stimulating food. It is prohibited for those who are allergic to this product and those with allergic constitution. If the patient has the need for medication, please follow the doctor’s instructions strictly under the diagnosis and treatment of a professional physician.