Precocious heart disease is a cruel “killer” that endangers the health and lives of children and adults. Precocious heart disease in children is caused by a disorder in the development of the heart during fetal life. The main causes are genetic and environmental factors. Precocious heart disease is a cruel “killer” that endangers the health and lives of children and adults. Premature heart disease in children is caused by a disorder in the development of the heart during fetal life. The main causes are genetic and environmental factors. However, parents should be alert and seek medical attention when the following symptoms appear in infants and newborns to exclude cardiovascular malformations. The common manifestations include persistent cardiac and respiratory malfunction after birth; persistent cyanosis or recurrent confusion; difficulty in breastfeeding and weight gain; detection of malformations other than the heart; recurrent “pneumonia”-like signs in the lungs, etc. Because children with precordial disease are often in poor health, have poor nutritional status, and have poor body defenses, they are prone to complications of infections and fever, and their condition evolves more quickly and severely. Repeated respiratory infections, in addition to fever, are prone to complications such as heart failure, which may delay treatment. Therefore, when fever occurs in children with prediabetes, it is important to seek medical attention and treatment in a timely manner. Normally, this kind of children should strengthen the care, patient feeding, warm and cold properly, try to prevent infection, in order to strive for the time of treatment and improve the quality of survival of the child.