Moles with red marks can be coated with recombinant human epidermal growth factor gel, polysulfonic acid mucopolysaccharide cream and other ointments. Red marks on moles belong to a normal physiological phenomenon, usually do not need to take measures to deal with it, and can gradually disappear with the passage of time. If the patient wants to promote the recovery of the skin lesion, recombinant human epidermal growth factor gel can be used topically under the guidance of a physician; polysulfotoxin mucopolysaccharide cream can also be applied to inhibit the formation of scars. In addition to the above medications, some people who have red marks after moles fall off the scabs can also be treated with topical application of creams such as retinoic acid cream and hydroquinone cream. Some patients can also apply mupirocin ointment, erythromycin ointment and other drugs to fight infection, which will help the skin lesions recover. It is recommended to follow the doctor’s instructions to use medication to treat moles with red marks after the scabs fall off, and not to use medication indiscriminately on their own. Daily attention to skin care, avoid foreign body friction stimulation, ultraviolet radiation.