If the widening of the inferior vena cava is congenital, such as compensatory widening of the inferior vena cava, there is no need for treatment, if it is due to thrombus dislodgement causing blockage of the inferior vena cava vessels. If the lumen is narrowed due to thrombosis, interventional embolization or stent implantation in the blocked inferior vena cava is required. If the various laboratory tests of the heart are normal and the patient does not have any discomfort, the widening of the inferior vena cava will not affect the health and can be reviewed regularly. If the results of various tests suggest cardiac insufficiency, it should be treated as heart failure, and the edema of lower limbs can be treated with oral hydrochlorothiazide. Chest tightness and shortness of breath can be treated with oral bisoprolol and other drugs that improve myocardial ischemia. Usually, a low-salt, low-fat diet and minimal activity can reduce the burden on the heart.