Myeloid leukemia, including acute myeloid leukemia and chronic granulocytic leukemia, is a malignant proliferative tumor occurring in the blood system. At present, the medical profession has not yet clarified the cause of its pathogenesis. In the following, it is described from the aspects of clinical manifestations, natural course and treatment. 1. Clinical manifestations often include anemia, bleeding and infection. 2. Acute myeloid leukemia progresses rapidly, while chronic granulocytic leukemia develops slowly and the spleen is enlarged. According to the course of the disease, it is divided into chronic stage, accelerated stage and acute stage. 3. The therapeutic drugs for acute myeloid leukemia include cytarabine and zorubicin, etc., while the therapeutic drugs for chronic granulocytic leukemia include imatinib and dasatinib, etc. Once abnormal blood counts occur, accompanied by bleeding, anemia, hepatosplenomegaly and other manifestations, it is necessary to go to regular hospitals in time and carry out standardized treatment under the guidance of physicians to avoid deterioration of the condition.