It is possible for ventricular septal defects to cause moderate mitral regurgitation, but it is a rare condition.
Ventricular septal defect is a common congenital heart malformation that results from a defect in the wall between the right and left ventricles. Moderate mitral regurgitation, on the other hand, reflects moderate blood regurgitation of the mitral valve due to incomplete closure.
1. Ventricular septal defects do not cause moderate mitral regurgitation: in most cases, small to medium-sized ventricular septal defects are asymptomatic and lead to generalized ischemic response only when the heart is not coordinated with blood exchange, such as in the case of strenuous exercise.
2. Ventricular septal defect can lead to moderate mitral regurgitation: when large ventricular septal defect or small and medium-sized ventricular septal defect causes functional hypertrophy of the heart secondary to prolonged strenuous exercise, it will indirectly widen the gap between the mitral valves, leading to mitral valve closure incompletion, triggering moderate mitral regurgitation.
In more serious cases of moderate mitral regurgitation due to ventricular septal defects, it is recommended to go to the hospital to receive regular treatment.