There is no such thing as the best treatment for lumbar spine 12th fracture clinically. It is necessary to choose the appropriate treatment according to the severity of the fracture, which generally includes conservative treatment and surgical treatment. 1. Conservative treatment: If the fracture is stable or not combined with other injuries such as subluxation or spinal cord injury, and there is no motor reflex disorder, sensory dysfunction or other abnormal manifestations, the fracture can be treated by bed rest on a hard bed, external fixation with plaster or support, and also with some Chinese medicines or ointment. 2. Surgery: When the fracture is unstable, combined with nerve and spinal cord injury, or has other abnormal manifestations, then it is necessary to consider surgical treatment, such as posterior lumbar decompression surgery, anterior lumbar internal fixation surgery, and bone cement plasty. When there is a fracture of the 12th lumbar vertebra, one should consult a doctor in time to rule out serious injury and receive regular treatment in time to avoid delaying the condition.