Hip joint pain when cold needs to be applied to the cause of the disease, such as non-steroidal anti-inflammatory drugs, immunosuppressants, glucocorticoids, anti-rheumatic, nutritive cartilage drugs, anticoagulants, lipid-lowering drugs and other types of drugs. It may be caused by ankylosing spondylitis, osteoarthritis, femoral head necrosis and other diseases. 1. Ankylosing spondylitis: non-steroidal anti-inflammatory drugs such as celecoxib, ibuprofen, meloxicam, and immunosuppressants such as etanercept and adalimumab, as well as anti-rheumatic drugs such as methotrexate and lorazepam. 2. Osteoarthritis: non-steroidal anti-inflammatory drugs such as acetaminophen and indomethacin can be applied, and glucocorticosteroids such as dexamethasone, prednisolone and methylprednisolone can be injected locally. Nutritional cartilage drugs such as glucosamine sulfate can also be used for treatment. 3. Femoral head necrosis: low molecular heparin, warfarin and other anticoagulants can be applied, as well as lipid-lowering drugs, such as lovastatin, simvastatin and so on. It is recommended that people who suffer from hip pain when it is cold should go to the hospital to do relevant examinations in time to clarify the cause of the disease, and follow the doctor’s instructions to actively treat the primary disease, and should not blindly use medication on their own to avoid delaying the condition.