S-100 usually refers to immunohistochemistry S-100. If S-100 is positive, the body may be experiencing neurological lesions such as nerve sheath tumors and neurofibromas. Immunohistochemistry S-100 is a common immunohistochemical marker in pathology diagnosis and is a nerve-specific protein. If S-100 is positive, it may be a human neurological disorder such as nerve sheath tumor and neurofibroma. In diagnostic pathology, S-100 is used as a marker for neurogenic tumors such as nerve sheath tumors and neurofibromas, as well as for malignant melanomas and some mesenchymal malignancies. Immunohistochemistry usually detects genes in cancerous tissue. Surgically removed cancerous tissue will be examined pathologically. A specimen of the cancerous tissue is made and the shape of the cancer cells is looked at under a microscope to determine the type of cancer. Patients who are positive for S-100 need to be diagnosed by the doctor in combination with the patient’s condition and the relevant test results, and then a reasonable treatment will be formulated and carried out.