Is diabetes related to obesity?

  Obese patients have a significantly higher risk of developing type 2 diabetes, with a 4-fold increase in the risk of diabetes in obese patients between the ages of 20 and 44. Clinical investigations have shown that the risk of developing diabetes is closely related to body mass index (BMI). the relative risk of developing diabetes is 42 times higher in men with a BMI ≥ 35 than in men with a BMI < 23. BMI appears to be the most important risk factor for type 2 diabetes, and even those with an average weight still have a significantly higher risk than those with a low weight.  Why are obese people prone to diabetes? Medical research suggests that obesity can cause insulin resistance, which may be related to the production of various cytokines by adipocytes that act on fat, liver or muscle, thus affecting insulin action. Obesity is often accompanied by hyperinsulinemia, where insulin causes insulin resistance by down-regulating insulin receptors.  Because the body is insensitive to insulin, the demand for insulin increases and the pancreatic beta cells must secrete more insulin to meet the needs of the muscle in order to keep blood glucose in the normal range. In order to adapt to this need, the long-term overload of pancreatic islet cells eventually leads to the failure of pancreatic β-cells and the development of diabetes.  The sensitivity to insulin in obese people can be changed, the key is to control the diet. Excessive intake of food is often one of the reasons for obesity. As long as the diet is strictly controlled and physical exercise is appropriately enhanced, the degree of obesity can be reduced and the sensitivity of the body to insulin can be improved, which is conducive to controlling the symptoms of diabetes and bringing blood sugar back to normal.  In addition to inducing diabetes, obesity is also associated with cardiovascular disease, hypertension, sleep apnea, colon cancer and gallbladder disease. Obesity should be seen as a disease that needs to be treated, rather than not starting treatment until complications arise.