Constipation in middle-aged people may be caused by dietary factors, indigestion, intestinal flora imbalance, intestinal polyps, intestinal obstruction, etc. General treatment, medication and surgery should be given according to their causes. 1. Dietary factors: if constipation is caused by eating too little dietary fiber, you can increase the intake of dietary fiber and drink more water to help defecation. 2. Indigestion: constipation caused by slow gastrointestinal peristalsis, you can follow the doctor’s instructions to take mosapride, itopride, pepsin and other drugs to increase gastrointestinal power; appropriate increase in the amount of exercise to stimulate intestinal peristalsis, which will help defecation; if necessary, take lactulose, polyethylene glycol electrolytes to soften the feces and promote defecation. 3. Intestinal flora imbalance: probiotics such as Saccharomyces boulardii and Bifidobacterium bifidum can be taken as prescribed by the doctor to promote the balance of intestinal flora, which can help defecation. 4. Intestinal polyps: polyps are large in size, causing constipation due to the obstruction of fecal discharge, you can consider removing the polyps under endoscopy. 5. Intestinal obstruction: Intestinal obstruction causes fecal matter to be unable to be discharged, and surgical treatment can be considered. If the constipation of middle-aged people can not be changed by self-adjustment, it is recommended to consult a doctor in time, and follow the doctor’s advice to actively treat.