Whether Kawasaki disease is cured after 2 years of being well depends on the situation. Generally, it can be considered cured, but there are some special cases. Kawasaki disease, or mucocutaneous lymph node syndrome, is a self-limiting disease with a favorable prognosis for most children. Children without coronary artery disease undergo a comprehensive examination (including physical examination, electrocardiogram, and echocardiogram) at 1, 3, and 6 months and 1 to 2 years after discharge from the hospital. If followed up regularly for 2 years, a comprehensive examination without abnormalities can generally be considered cured. However, it should be noted that there are some special cases, such as recurrence, and there is a 1% to 2% recurrence rate of Kawasaki disease. In addition, some children without effective treatment may develop coronary artery disease in about 10% to 20%, and should be followed up regularly. Coronary artery disease occurs in 10% to 20% of children without effective treatment, and should be closely followed up for a long time, every 6 to 12 months. Attention to Kawasaki disease coronary artery dilatation or coronary artery aneurysm most of the disease in 2 years after the disappearance of their own, but often left wall thickening and elasticity weakening and other functional abnormalities. Huge coronary aneurysms are often not easy to disappear completely within 2 years, which can lead to thrombosis or lumen narrowing, requiring regular follow-up, surgical intervention if necessary, and postoperative recurrence. It is recommended to seek timely medical treatment for standardized consultation and diagnosis.