Autosomal recessive limb-girdle dystrophy (LGMD type 2) is one of the types of limb-girdle muscular dystrophy (LGMD) typed according to the mode of inheritance, and it is a common hereditary muscle disease. Autosomal recessive limb-girdle muscular dystrophy can be subdivided into LGMD2A (autosomal recessive limb-girdle muscular dystrophy type A), LGMD2B (autosomal recessive limb-girdle muscular dystrophy type B), LGMD2C (autosomal recessive limb-girdle muscular dystrophy type C) and other types. LGMD2A is one of the most common subtypes of LGMD, which is more common in children or adults with early onset of the disease. Most of the patients show mild to moderate progressive limb weakness, with the lower limbs being heavier than the upper limbs, which is clinically characterized by the “duck step” and excessive spinal scoliosis, and contractures of the hip, knee, and elbow joints can appear rapidly. LGMD2C is one of the most severe subtypes, mostly starting in children, and its progression is often rapid, with most patients losing the ability to walk 10 years after the onset of the disease, and most of them dying before the age of 29. When the diagnosis of autosomal recessive limb-girdle dystrophy is confirmed, the patient should go to a regular hospital and be treated under the guidance of a doctor.