The small white particles appearing on both sides of the nose are often considered to be the manifestation of acne, and there may also be lipid particles, which need to be specifically analyzed. 1. acne: the formation of acne has many reasons, such as patients with endocrine disorders, pore blockage, dietary stimulation, severe skin keratinization, sebum metabolism abnormalities, irregular work and rest, etc., acne is in the superficial skin, easy to secondary infection to form pustules. 2. Lipid granules: the distribution of sebaceous glands on both sides of the nose is relatively dense, when the patient’s body is active in oil secretion due to diet, life and other reasons, there will be a large amount of oil deposits on both sides of the nose, manifested as fat granules. Commonly found in people with oily skin, they need to adjust their lifestyle in time and do a good job of facial cleansing. There may be other reasons for the small white particles on both sides of the nose, so patients are advised to go to the hospital for treatment according to the medical history and examination results.