There are three main types of drugs used to treat premature ejaculation, namely 5-hydroxytryptamine reuptake inhibitors, tricyclic antidepressants, and topical prolongation drugs. 1. 5-hydroxytryptamine reuptake inhibitors: these drugs are mainly used to improve the ejaculatory control of the central nervous system by increasing the level of 5-hydroxytryptamine neurotransmitter. Commonly used drugs are dapoxetine, paroxetine, sertraline and so on. 2. Tricyclic antidepressants: If the patient himself suffers from depression, it is possible to cause sexual dysfunction. Sexual dysfunction caused by depression includes impotence, premature ejaculation, ejaculation disorder, and reduced sexual pleasure and interest. It can be treated with drugs such as clomipramine and trazodone. 3. External delay drugs: For patients whose penis or glans is too sensitive and leads to premature ejaculation, external delay drugs can also be used to reduce sensitivity, so as to improve the purpose of premature ejaculation. Commonly used topical delay drugs are dacronin, lidocaine, etc., need to pay attention to, if the use of topical delay drugs, be sure to wear a condom correctly, so as not to cause injury or irritation to the partner. Premature ejaculation may be caused by a variety of reasons, it is recommended that patients go to the hospital for relevant examinations to clarify the cause of the disease before treatment. It is recommended that patients do not use drugs to treat premature ejaculation, in order to avoid improper use of medication on the body, if you need to use medication, but also under the guidance of the doctor to strictly comply with the medical advice to use.