Intercostal neuralgia will not hurt for life, the duration depends on the cause and should be analyzed on a case-by-case basis. Common causes include herpes zoster, thoracic spine tuberculosis, ankylosing spondylitis and other diseases. 1. Herpes zoster: Intercostal neuralgia caused by herpes zoster can be controlled by using medications such as acyclovir and carbamazepine under the guidance of a doctor. The duration of intercostal neuralgia after shingles will be longer. 2. Thoracic spine tuberculosis: Intercostal neuralgia caused by thoracic spine tuberculosis is recommended to be treated with medications such as isoniazid and rifampicin under the guidance of a doctor, and surgical treatment is necessary to achieve therapeutic results. Intercostal neuralgia caused by thoracic spine tuberculosis is caused by the invasion of intercostal nerves, which is usually related to the degree of control of tuberculosis, and gets better with the improvement of tuberculosis. 3. Ankylosing spondylitis: Intercostal neuralgia caused by ankylosing spondylitis is usually treated with medication and surgery. Medications such as celecoxib and methotrexate can be administered under the guidance of a doctor to treat intercostal neuralgia, and surgical treatments, such as orthopedic spine surgery, can be performed if necessary. Symptoms of intercostal neuralgia can be relieved after surgery. Intercostal neuralgia can also be caused by other conditions, it is recommended to seek medical attention to identify the cause and actively treat the condition to avoid delays.