Taking febuxostat for a month and then gout may be due to insufficient dosage of medication, not strictly avoiding food, strenuous exercise and other factors, need to further clarify the cause to be dietary adjustments, appropriate rest or adjust the treatment program and other measures. 1. Insufficient dosage: Febuxostat mainly reduces blood uric acid level by inhibiting the production of uric acid. If patients do not go to the hospital for review after taking Febuxostat or do not adjust the dosage of Febuxostat according to the results of the review, it may lead to poor control of blood uric acid and induce gout. NSAIDs such as indomethacin, etoricoxib or colchicine can be used to relieve the symptoms under doctor’s guidance, and the medication regimen can be adjusted after the symptoms are relieved. 2. No strict dietary restrictions: gout patients need to strictly low purine diet, while quitting smoking, alcohol, such as patients are not strict dietary restrictions, taking febuxostat still eat seafood, broth and other high-purine diets or alcohol, may lead to gout again, this time, in addition to analgesic and symptomatic treatment, the patient needs to be further dietary restrictions and appropriate adjustment of dietary habits. 3. Strenuous exercise: gout patients taking febuxostat during the strenuous anaerobic exercise may lead to enhancement of nucleic acid metabolism, leading to fluctuations in the body’s blood uric acid level, triggering an acute attack of gout. Patients can adjust the intensity of exercise, acute attacks try to bed rest. Taking febuxostat for a month and again gout may have other reasons, it is recommended that the patient to the relevant departments of the regular hospital for detailed consultation, and comply with the doctor’s instructions to use medication.