Mirabelone can and tamsulosin can generally be taken together, but should be taken under medical supervision, but also pay attention to the contraindications of the drug and adverse reactions and other matters. Mirabelone has the effect of relaxing the smooth muscle of the bladder and is indicated for the treatment of adults with overactive bladder with symptoms of urinary urgency, frequency and/or urge incontinence. Tamsulosin hydrochloride also functions as a selective alpha1 adrenoceptor blocker with bladder smooth muscle relaxation and is indicated for the treatment of dysuria problems caused by prostatic hyperplasia. Mirabelone and therapeutic doses of tamsulosin hydrochloride generally do not have drug interactions, and if prostatic hyperplasia with overactive bladder syndrome is present, it is possible to combine treatment with both of these medications. However, the drugs should be used together under the supervision of a physician, as directed by the doctor. Contraindications to the use of Mirabelone include hypersensitivity to the product, poorly controlled severe hypertension (systolic blood pressure of 180 mmHg and above and/or diastolic blood pressure of 110 mmHg and above). Common adverse reactions to the drug include nausea, constipation, diarrhea, urinary tract infection, tachycardia, dizziness, and headache. Contraindications to the use of tamsulosin hydrochloride include hypersensitivity to the product and children. Adverse drug reactions include diarrhea, constipation, nausea, vomiting, dizziness, pruritus, and rash.