Most of the joints of the whole body click, most of the physiological factors, but also may be pathological factors such as osteoarthritis, osteoporosis and so on. Physiological factors generally do not require special adjustments, if the pathological factors need to address the cause of the treatment. Physiological factors cause the whole body joints clicking, we should pay attention to change the daily life style, avoid the local excessive strain and stress, and at the same time carry out appropriate functional exercises, such as the functional exercise of the waist and back muscles. Osteoarthritis needs to be treated with physiotherapy and drugs that nourish joint cartilage, such as glucosamine sulfate. Normally, it is necessary to avoid weight-bearing and stress on the lesion area, such as avoiding climbing stairs and mountains, and at the same time, pay attention to keeping warm and avoiding getting cold. Osteoporosis needs appropriate calcium supplementation, attention to balanced nutrition, adequate sunshine, regular exercise, etc. to help the health of bones and muscles. The first thing to do is to identify the cause of joint clicking, pathological factors should be timely to the hospital, in accordance with the doctor’s instructions standardized treatment.