What is the root cause of ED? In other words, the cause of ED, (if you want to use a short text to clarify the issue, it is impossible) to the bottom line, there are two major factors: psychogenic and organic, and sometimes a mixture of the two. If we look at the progression of age as the main axis, the psychogenic factor is dominant in young people, and the organic factor is dominant in middle-aged and old people. Here “organic” also includes genital malformations, penile vascular and neurological lesions, trauma and medically induced side injuries, etc., but here the emphasis is on age-related LOH lesions (late-onset hypogonadism in men); “psychogenic” is not It is not that there is no material basis for the lesion, but that our previous medical research was insufficient to detect it and thus attributed it to “psychogenic”. In fact, it has been observed through current research that some of the previous psychogenic sexual dysfunctions are related to functional changes in the secretion, uptake and transmission of neurotransmitters, but some are reversible, while some gradually evolve into irreversible or organic ones.