Anal fissures usually have a small amount of blood in the stool, mainly in the form of blood on the paper after the stool, and in severe cases, occasional dripping or spraying of blood. The treatment of anal fissure blood in stool includes: 1) keeping the stool open and preventing constipation; 2) medication: including oral medication and local medication, local medication including sitz bath, plugging and creaming; 3) surgery: for old anal fissures or those with large arterial blood vessel injury with high bleeding volume if medication is not effective. The specific medication should be combined with the clinical situation and guided by the doctor’s interview.