Functional dyspepsia, formerly known as non-ulcer dyspepsia, is a group of dyspeptic syndrome without organic lesions or only general chronic gastritis, which can be recurrent or persistent, and is common in young and middle-aged people. This disease is quite common, and data show that it accounts for about 30% of the total number of internal medicine outpatient clinics and 40% to 50% of gastroenterology outpatient clinics. As this disease often exists together with chronic gastritis, according to gastroscopy statistics, about 50% of functional dyspepsia is accompanied by chronic gastritis, but the number and severity of its symptoms are not consistent with the degree of gastritis, so scholars at home and abroad tend to include the symptoms of such chronic gastritis in the scope of functional dyspepsia, and the treatment is basically the same. The etiology and pathogenesis of functional dyspepsia are not well understood and may be the result of a combination of factors, with more women than men among the patients. Investigation and research found that patients with this disease often have abnormal personality, anxiety, depression, and higher-than-normal hypochondriacal points, and the frequency of stressful events in their lives is also significantly higher than normal people. Treatment effect and psychological factors also have a significant relationship, it is reported that the efficiency of treatment with placebo can reach 30% to 60%, so doctors should pay great attention to the role of psychological factors in the treatment of patients. There are three principles of pharmacological treatment of functional dyspepsia, one is the use of drugs to be targeted, according to its prominent symptoms, from the perspective of pathophysiology of drug selection. Second, to reflect the principle of individualized treatment. Third, advocate intermittent medication and avoid long-term medication. Most patients can be treated for 2 to 4 weeks, and only a few patients need longer treatment. The most common symptom among our patients is epigastric distension and fullness, which is a type of gastric motility disorder, and the medication should be mainly pro-gastric motility drugs, such as morpholine, mosapride, etc. A small number of patients with upper abdominal pain as the main manifestation, ulcer-like type, should be mainly acid suppressants, such as omeprazole, famotidine, ranitidine, etc.. Gastric mucosal protective agents such as aluminum thioglycollate, Daxil, etc., although also commonly used, but in a secondary position, because most of the current data show that such drugs for functional dyspepsia, its efficacy and placebo comparison is basically the same. Psychological treatment and anti-anxiety drugs: most of these patients will do gastroscopy, colonoscopy, less than once or twice, more than seven or eight times gastroscopy, but the results are various types of “superficial gastritis”, such patients are treated according to the stomach or intestinal disease itself, I have a few more typical patients have been taking drugs for more than twenty years of gastric disease, and in more than twenty years to eat carefully, and still not well The result is that after the psychotherapy and anti-anxiety medication, they are better, they are fatter, and they have more courage to eat, why? Because it is not a real gastric disease, according to the organic gastric disease to treat certainly not, so the effect received is very different, such patients usually have sleep problems, the gastrointestinal tract is a little too much attention. Always worry about this and that. They are afraid that they have developed or will develop gastrointestinal tumors in the future. Of course cancer is scary, but not having cancer and waiting for it to come is even more painful. When I go to the doctor, I hope I am not sick, but when the doctor says no major problem is found, I will have doubts about the doctor and I like to go around to the doctor. Our department has been studying the treatment of persistent chronic gastrointestinal dysfunction for many years, especially in psychological diagnosis and psychotherapy, and has accumulated some experience and formed a specific reattribution-cognitive-medication holistic treatment model for gastrointestinal diseases. The therapeutic effect is remarkable. Chronic gastritis in China is mainly caused by Helicobacter pylori, and it has been controversial whether this bacterium should be eradicated across the board. For this reason, the 2000 National Consensus Opinion on chronic gastritis made four recommendations appropriate for H. pylori eradication: 1. Chronic gastritis with significant abnormalities (mucosa with erosion, moderate to severe atrophy and intestinal hyperplasia, heterogeneous hyperplasia). 2, with a family history of gastric cancer. 3.With erosive duodenitis. 4.Persons with poor efficacy of conventional treatment for indigestion symptoms. The fourth article above is for functional dyspepsia with chronic gastritis. Although the detection rate of H. pylori in patients with functional dyspepsia is about 65% to 75%, the presence of this bacterium is not clearly associated with the appearance of functional dyspepsia symptoms. The role of H. pylori in the development of functional dyspepsia needs to be further investigated. Therefore, eradication of H. pylori in functional dyspepsia is only an experimental treatment and does not play a major role in the overall treatment plan.