Waking up from sleep with back pain may be caused by physiological reasons, lumbar dorsal musculoskeletal fasciitis, lumbar disc herniation and other factors, which can be treated by medication, physical therapy, surgery and other methods under the guidance of the doctor. 1. Physiological reasons: may be the temperature is too low, poor sleeping posture, etc., are easy to cause the lumbar muscle spasm, resulting in waking up in bed back pain, can use diclofenac sodium extended-release tablets, celecoxib capsules, and other drugs for relief. 2. Lumbar dorsal myofasciitis: patients due to long-term stooping labor, resulting in lumbar dorsal myofascial strain, aseptic inflammation, can be treated by physical therapy, such as infrared therapy, microwave therapy, etc., in order to alleviate the pain in the lower back. 3. Lumbar disc herniation: after the disc herniation, it is easy to stimulate the surrounding tissues and produce inflammatory reaction, which can be treated by surgery, such as radiofrequency ozone ablation, lumbar foramen ovale surgery and so on. Patients who wake up from sleep with back pain should go to the regular hospital in time, and give the correct treatment under the guidance of the doctor after clarifying the cause of the disease.