Scleroderma refers to the following diseases: 1. Scleroderma: a connective tissue disease caused by increased and thickened collagen fibers in the dermis, which can be treated clinically with topical halometasone ointment or fluticasone propionate cream and oral colchicine or nifedipine tablets; 2. Neurodermatitis: a tougher texture of plaques and moss-like changes can occur, which can be treated clinically You can choose halometasone ointment or fluticasone propionate cream topical application, with dimethylsilicone oil or vitamin E ointment, and oral administration of olopatadine hydrochloride tablets or loratadine citrate capsules, combined with compound glycyrrhetinic acid capsule. According to the above mentioned scientific and systematic treatment, the eradication of both diseases can be achieved.