For patients who develop gonococcal disease, the current clinical pharmacological treatment is mainly based on the physician’s choice of initial antibiotics according to an empirical protocol. For patients who do not develop complications such as hematogenous dissemination, their first choice of medication is ceftriaxone and daikonin. Subsequently, if the efficacy is poor or the infection worsens or even infects adjacent parts of the affected area, the medication needs to be adjusted, commonly cefotaxime, cefotetan, ciprofloxacin, and ofloxacin. In case of infection during pregnancy, ceftriaxone sodium can be used for treatment. Generally gonococci are present in the leukocytes of purulent secretions from acute urethritis and cervicitis, and are human parasites. Gonococcal infection is often transmitted through sexual contact and is mainly manifested as a purulent infection of the genitourinary system, often called gonorrhea. It is recommended that the patient’s sexual partners be treated together to avoid cross-infection. After gonococcal infection is diagnosed, it should be treated promptly and in strict compliance with medical prescriptions for regular and adequate medication in order to control the disease and avoid disseminated gonococcal infection, which is rare but may be life-threatening. In addition, when gonorrhea patients have disappeared after a period of standardized medication, such as frequent, urgent and painful urination, laboratory tests such as gonococcal culture can be performed as prescribed by the doctor. If the results show that no gonococcus is found, this may indicate a cure.