Minimally invasive laparoscopic splenectomy splenectomy is one of the effective treatments for ITP. The efficiency of splenectomy is up to 70-90%, and the postoperative recurrence rate is 9.6-22.7%. The long-term results are 50-60%. Indications: ① Chronic ITP with 6 months of active medical treatment is ineffective; ② Poor efficacy of adrenocorticotropic hormones or those who need to be maintained with higher doses (30-40 mg/d); ③ Contraindication to hormone or immunosuppressive applications; ④ 51Cr marker platelet examination, if platelets are mainly blocked in the spleen, the splenic efficiency is up to 90%, if blocked in the liver, 70% of splenectomy is ineffective. At this stage, there are generally two reasons that cause patients to be reluctant to accept, splenectomy, surgical treatment, the previous method, the surgical incision is very about a foot long, after surgery, even after recovery also leaves a lot of trauma and scars, often making it difficult for patients to accept, the second reason is the doctor side, with the social environment, ideology and economic views, so I here, often encounter, the condition is so serious that Therefore, I often encounter patients who have to take splenectomy surgery when the patient’s surgical condition is already very poor, which increases the patient’s surgical risk and treatment cost. In fact, theoretically, the first step in the treatment of ITP is hormone therapy, the second step is splenectomy surgery, and the third step is immunotherapy, but in reality, the clinical situation is that splenectomy is the last treatment option, which makes many ITP patients go through a very tortuous treatment path. Even if medication is still needed? It requires significantly less dose and variety, therefore significantly reducing the cost and difficulty of treatment. Nowadays, laparoscopic minimally invasive splenectomy is the greatest blessing for ITP patients. This surgery, which requires only 0.5 to 1 cm, 4 small incisions in the abdomen, can be completed with almost no bleeding, and there is no obvious surgical scar in the abdomen after surgery, which significantly reduces postoperative complications, and the impact on life and work after surgery, is also significantly reduced. It also offers the possibility of splenectomy for patients with severe platelet decline prior to surgery.