People often say “toothache is not a disease, but it is a pain that kills people”, which reflects that toothache has a great impact on people’s health and spirit, toothache is the most common symptom of oral diseases, which can be caused by many diseases such as tooth decay (worm teeth), acute and chronic pulpitis, periodontitis, acute and chronic apical periodontitis, dentin allergy, hidden tooth fracture or root fracture. The toothache caused by dental caries (worm teeth) is because there is a cavity in the tooth, and the toothache can be felt when encountering cold, hot, sour or sweet stimulation or when food is embedded in the cavity; the toothache caused by acute and chronic pulpitis can be stopped when the stimulus is removed; the toothache caused by acute and chronic pulpitis is spontaneous, paroxysmal pain, and the pain increases when encountering hot and cold stimulation or resting at night; the toothache caused by deep cavity, deep periodontal pocket, etc., the patient usually cannot clearly put forward the location of the affected tooth. The toothache caused by deep cavity, deep periodontal pocket, etc., the patient usually can not clearly put forward the location of the affected tooth, and the toothache can last for a long time after the stimulus is removed. The performance of persistent pain, accompanied by gum redness and swelling, bleeding and pus overflow, and even loose teeth, gum atrophy; toothache caused by acute and chronic periapical inflammation, the performance of persistent throbbing pain, teeth have a sense of elongation or floating, can not chew food, toothache caused by oral diseases. “The only effective way to stop the pain is to go to dentistry for treatment. Other diseases that can induce toothache include trigeminal neuralgia, osteomyelitis of the jaws, dry socket, pericoronitis of wisdom teeth, acute suppurative maxillary sinusitis, malignant tumor of the jaws and gums, tooth-containing cyst of the jaws, upper respiratory tract infection, heart disease, leukemia, neurasthenia, etc., which should be treated symptomatically.