The difference between AIDS red spot and eczema lies in the pathogenesis, lesion manifestation, progression of the disease and treatment modality. 1. Pathogenesis: AIDS red dots, i.e., skin lesions in the acute phase of AIDS, are bleeding spots on the skin caused by HIV infection; eczema is an inflammatory skin disease of the epidermis and superficial dermis caused by a variety of internal and external factors, and it is due to the stimulation of inflammation to appear as skin lesions, which are manifested as red dots. 2. Skin lesion performance: the diameter of the rash in the acute infection stage of AIDS is very small, mostly less than two millimeters, and will not protrude from the surface of the skin; while the diameter of eczema is often more than two millimeters. 3. Progress of the disease: most of the rashes in the acute infectious stage of AIDS will disappear within one month; eczema will spread to the surrounding area over time and the boundary is not very clear, in addition, there are signs of oozing. 4. Treatment: Once AIDS is diagnosed, active antiretroviral treatment is needed; topical corticosteroids, such as hydrocortisone butyrate ointment, can be used for eczema. If you suspect that you are infected with HIV, you should go to a regular hospital in time, and not make blind judgments on your own.