According to the drug’s instruction manual, taking aspirin is generally able to take erythromycin. Aspirin and erythromycin belong to different classes of drugs, and there is no risk of overdose when they are taken together; moreover, the instructions for the drug do not explicitly mention the prohibition of taking the two drugs together. Therefore, aspirin is generally able to take erythromycin. Please follow your doctor’s instructions for specific medications. 1. Aspirin is a commonly used antiplatelet drug, which inhibits the action of thromboxane A2 (TXA2) by inhibiting the action of cyclooxygenase-1 (COX-1), thus inhibiting platelet aggregation. It is used for the treatment of angina pectoris, prevention of deep vein embolism or pulmonary embolism, and rheumatoid arthritis. Adverse reactions such as abdominal pain, bleeding, and nausea may occur after taking the drug. It is contraindicated for those who are allergic to aspirin or other salicylates, active ulcers, hemophilia, thrombocytopenia, severe renal failure, severe hepatic failure, severe cardiac failure. 2. Roxithromycin is an artificial semi-synthetic macrolide antibiotic, which can achieve bactericidal effect by inhibiting protein synthesis of bacterial ribosomes. It is suitable for the treatment of respiratory tract infections and genitourinary tract infections caused by pathogens sensitive to Roxithromycin. Adverse reactions such as abdominal pain, nausea, vomiting, rash and headache may occur after taking the drug. It is contraindicated for those who are allergic to roxithromycin or other macrolides. Combination with drugs containing ergotamine or dihydroergotamine is prohibited. Take care to use the drug under the supervision of a physician.