Amlodipine causes bleeding gums can be replaced with other blood pressure-lowering drugs. Clinically, amlodipine belongs to dihydropyridine calcium antagonist; after taking it, it can inhibit calcium ions from entering the vascular smooth muscle across the membrane as well as the cardiac muscle, so as to reduce the peripheral vascular resistance as well as the blood pressure, which is mainly used for the treatment of hypertension and coronary heart disease. Usually the drug after taking may appear edema, dizziness, flushing, bleeding gums, arthralgia and other uncomfortable symptoms; when there are gums out of the gums lead to bleeding gums, to immediately stop using the drug and timely consult the doctor, in the doctor’s comprehensive assessment after the replacement of other antihypertensive drugs for treatment. Usually can be replaced with fosinopril. Drugs such as valsartan, which reduces extracellular volume, lowers peripheral vascular resistance, or inhibits myocardial contractility and slows the heart rate, which leads to a decrease in blood pressure. It is contraindicated for those who are allergic to the components of the drug, while it is used with caution in cases of hypotension, aggravation of angina, myocardial infarction, while pregnant and lactating women are required to use the drug under the supervision of a doctor. If the symptoms of bleeding gums appear after taking amlodipine antihypertensive treatment, it is recommended to consult the cardiovascular internal medicine department in time, and adjust the medication program after the doctor’s comprehensive assessment of the condition.