As the saying goes, “medicine is three parts poisonous, no poison is not medicine”, and the instructions of the “cure” for wind-like off listed a lot of possible side effects. The chance of side effects during the treatment of these drugs is like winning the lottery and is not relevant to most people. The safety of these drugs is guaranteed if they are taken under the guidance of a doctor. However, some patients are afraid to take or reduce the dosage after reading the drug instructions and fail to control the progression of the disease within 2 years after the onset of the disease and suffer from structural joint damage. Some patients who have received regular combination therapy and are in clinical remission think they are well and stop taking the medication. These poor outcomes occur, sadly Modern medical concepts suggest that the goal of treatment of anaplasmosis is to maximize the relief of joint swelling and pain, prevent joint deformity, and help maintain normal motor function. Drug therapy is a central part of the treatment regimen for this disease. Existing therapeutic drugs are divided into three main categories – “symptomatic drugs” (anti-inflammatory and analgesic drugs, non-steroidal anti-inflammatory drugs), “curative drugs” (disease-modifying anti-rheumatic drugs), and “hormones” (glucocorticoids). With the development of modern medical science, on the basis of the traditional “cure” (chemically synthesized small molecule drugs), a variety of biologic “cure” (genetically engineered synthetic large molecule drugs) have been successfully developed in the past 20-30 years, making the prognosis of rheumatoid arthritis significantly improved. The prognosis of the disease has been significantly improved. The traditional rheumatoid drugs include methotrexate, leflunomide, salazosulfapyridine, chloroquine and hydroxychloroquine, which can reduce the activity of the disease and delay the damage of the joint structure, i.e., help to stop the development of the disease, so they are called “disease-modifying anti-rheumatic drugs”. They are called “disease-modifying antirheumatic drugs”. They are also called “slow-acting antirheumatic drugs” because of their long onset of action, which often takes weeks or even months to appear. The common feature of these drugs is that they are all borrowed from drugs used to treat other diseases for rheumatoid arthritis, so there is no indication for “rheumatoid arthritis” in the drug description. For example, methotrexate was originally an antineoplastic drug, whose side effects include liver function damage, mouth ulcers, leukopenia, etc.; Leflunomide was originally an insecticide, but was later found to have immunosuppressive effects, whose side effects include skin itching, hair loss, liver function damage, leukopenia, etc.; Salazosulfapyridine was originally used to treat ulcerative colitis, whose side effects include gastrointestinal reactions, allergy (rash), etc.; Chloroquine and hydroxychloroquine were originally used to treat malaria. Chloroquine and hydroxychloroquine were originally used for the treatment of malaria. Chloroquine has retinal accumulation toxicity and affects vision, and is now less commonly used. Hydroxychloroquine may affect the regulation of extraocular muscles and cause reversible blurred vision. Overall, hydroxychloroquine has the best safety profile and can be continued even during pregnancy, but its anti-rheumatoid effect is also the weakest. The new rheumatoid “cures”, represented by biologics, mainly include Ixepro or Enzyme, Classic, and Xumel, which are highly selective in blocking the pathogenic tumor necrosis factor (TNF), and Yamiro, which is highly selective in blocking the pathogenic interleukin-6 (IL-6). Their common feature is that they are all protein-based drugs, produced by genetic engineering technology, so they are called “biologics”, which are ineffective when taken orally and must be administered by injection. Compared to traditional “cures”, biologic “cures” generally work within a few days and are significantly stronger and more effective in preventing structural damage to the joints. The main side effect is a slightly increased risk of secondary infection, especially in patients with a history of tuberculosis who may experience a recurrence of tuberculosis after the application of biologics. Its main disadvantage is its expensive price, which makes it difficult to be used universally in most patients. In addition to the great progress made in recent years in the treatment of tuberculosis, the medical concept of treatment of tuberculosis has also changed dramatically, i.e., early treatment with a combination of 2-4 “curative drugs” (even prednisone), depending on the activity index and risk factors for poor prognosis, and regular follow-up during the treatment process to adjust the treatment in a timely manner. The type and dosage of drugs should be adjusted in a timely manner to suppress the disease as much as possible in the early stage of the disease, and after the disease is in remission, the doctor will gradually reduce and withdraw the drugs with relatively large toxic side effects. Due to the limitations of medical science and technology, it is not yet possible to completely cure or eradicate the disease. Therefore, after the disease has been remitted, it is still necessary to keep 1-2 “cure drugs” to continue the consolidation treatment to avoid the recurrence of the disease. It is a chronic, progressive, destructive arthritis that requires lifelong treatment. With the development of medical science, significant progress has been made in the treatment of arthritis with drugs and treatment strategies. It is entirely possible for patients to achieve clinical remission (the disease basically does not progress) and live with the disease as long as they adhere to reasonable treatment for a long time.