Loss of sensation in the medial calf is one of the symptoms of a high level femoral nerve injury. High femoral nerve injury presents as loss of sensation in the anterior medial femur and medial calf. Muscle and joint position sensation, motion sensation, and vibration sensation. If the nerve fiber that conducts deep sensation or the sensory center of the brain is damaged, muscle and joint position sensation and motion appear. Gunshot wounds, stab wounds, and medically induced injuries are common. Loss of sensation in the lateral calf and dorsum of the foot is one of the findings in the diagnosis of common peroneal nerve injury. Diagnosis of common peroneal nerve injury: history of injury, due to paralysis of calf extensor group and peroneal long and short muscles, showing foot drop inversion, loss of sensation in the lateral calf and dorsal foot …… loss of sensation in the medial calf is one of the symptoms of high femoral nerve injury. Femoral nerve injury high injury. Loss of medial calf sensation should be noted and the following diseases differential diagnosis: 1. Loss of anterior medial femoral and medial calf sensation High-level injury in femoral nerve injury manifests as loss of anterior medial femoral and medial calf sensation. Low-level injury, can be a simple saphenous nerve injury, showing medial calf sensory deficit. The femoral nerve originates from the lumbar plexus and travels down the surface of the iliacus muscle, penetrating the inguinal ligament and dividing into anterior and posterior strands 3-4 cm lateral to the femoral artery, innervating the suture and quadriceps muscles, with a cutaneous branch to the anterior femur and a saphenous nerve innervating the skin of the medial calf. Femoral nerve injuries are rare and mostly surgical. The main clinical manifestations after injury are impaired knee extension and sensory impairment of the anterior femur and medial calf due to quadriceps paralysis. If it is a surgical injury, it should be repaired as soon as possible. 2.Lateral calf and dorsal foot sensory loss Lateral calf and dorsal foot sensory loss is one of the results of the diagnosis of common peroneal nerve injury. The diagnosis of common peroneal nerve injury is mainly based on the history of injury, due to paralysis of the calf extensor group and peroneal long and short muscles, showing foot drop inversion, loss of sensation in the lateral calf and dorsalis pedis. Electromyography can determine the injury and the extent of the injury.